FIGURE

Fig. 6

ID

ZDB-FIG-250829-31

Publication

Li et al., 2025 - Reelin/Disabled-1 Signalling Contributes to Functional Recovery on Zebrafish After Spinal Cord Injury

Other Figures

All Figure Page

Back to All Figure Page

Fig. 6

Immunohistochemical analysis of motor neuron numbers in cross-sections of spinal cords caudal to the lesion site at 60 h after SCI in Reelin MO–, Dab-1 MO– and control MO–treated larvae. (A) Micrographs show DAPI staining (left panel, blue) and Islet 1–positive motor neurons (middle panel, red) being merged (right panel) at 40× magnification. Arrowheads denote Islet 1–positive motor neurons. Scale bar, 50 μm. (B) Quantification of numbers of Islet 1–positive motor neurons in spinal cord sections after treatment with Reelin, Dab-1 and control MOs. Data are from 60 sections per group. Five sections were analysed per animal and 12 animals were in each group in three independent experiments. Data represent means ± SEM, SCI plus Con MO versus all groups, ***p < 0.001, one-way ANOVA with Tukey's post hoc test.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT WT + MO1-dab1a WT + MO2-dab1a WT + MO2-reln WT + MO3-reln
Condition:	transection: spinal cord
Knockdown Reagents:	MO1-dab1a MO2-dab1a MO2-reln MO3-reln
Observed In:	motor neuron regeneration spinal cord motor neuron
Stage:	Day 6

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Int. J. Dev. Neurosci.