FIGURE

Fig. 9

ID

ZDB-FIG-250807-66

Publication

Misra et al., 2025 - Tirzepatide mitigates cognitive decline in zebrafish model of type 2 diabetes mellitus induced by high-fat diet

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Fig. 9

Effect of TZP oncognitive impairment in zebrafish in old and young age group in inhibitory avoidance test, A Time spent in light zone; B Time spent in dark zone. The statistical data analysis is presented by two-way ANOVA analysis by employing the Bonferroni post-test. The results showed that the time spent in the light zone was increased after the administration of TZP in both age groups of zebrafish and mitigated the effect of HFD significantly. Values presented as mean ± SD (p < 0.05), a vs. control, TZP (10 nM) per se, b vs. HFD, c vs. HFD + TZP (10 nM/kg) in both age groups. Values presented as mean ± SD (p < 0.05), α vs. HFD (young age group), β vs. HFD + TZP (young age group), γ vs. HFD + DPZ (young age group) (n = 12). A [F (4, 110) = 0.70, p = 0.5960], B [F (4, 110) = 0.82, p = 0.5145]

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Naunyn-Schmiedeberg's Arch. Pharmacol.