FIGURE

Fig. 12

ID

ZDB-FIG-250807-69

Publication

Misra et al., 2025 - Tirzepatide mitigates cognitive decline in zebrafish model of type 2 diabetes mellitus induced by high-fat diet

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Fig. 12

Effect of TZP oncognitive impairment in zebrafish in old and young age groups in novel tank diving test, A Time spent in top zone; B Time spent in bottom zone. After treatment with TZP and DPZ time spent in the bottom zone was significantly decreased and time spent in the top zone was significantly increased in both the young and old age groups of zebrafish as compared to HFD group. The statistical data analysis is presented by two-way ANOVA analysis by employing the Bonferroni post-test. Values presented as mean ± SD (p < 0.05), a vs. control, TZP (10 nM) per se, b vs. HFD, c vs. HFD + TZP (10 nM/kg) in both age groups. Values presented as mean ± SD (p < 0.05), α vs. HFD (young age group), β vs. HFD + TZP (young age group) (n = 12). A [F (4, 110) = 0.11, p = 0.9776], B [F (4, 110) = 1.36, p = 0.2522]

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Naunyn-Schmiedeberg's Arch. Pharmacol.