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Fig. 9 Effect of TZP oncognitive impairment in zebrafish in old and young age group in inhibitory avoidance test, A Time spent in light zone; B Time spent in dark zone. The statistical data analysis is presented by two-way ANOVA analysis by employing the Bonferroni post-test. The results showed that the time spent in the light zone was increased after the administration of TZP in both age groups of zebrafish and mitigated the effect of HFD significantly. Values presented as mean ± SD (p < 0.05), a vs. control, TZP (10 nM) per se, b vs. HFD, c vs. HFD + TZP (10 nM/kg) in both age groups. Values presented as mean ± SD (p < 0.05), α vs. HFD (young age group), β vs. HFD + TZP (young age group), γ vs. HFD + DPZ (young age group) (n = 12). A [F (4, 110) = 0.70, p = 0.5960], B [F (4, 110) = 0.82, p = 0.5145]