Fig. 6
- ID
- ZDB-FIG-250807-63
- Publication
- Misra et al., 2025 - Tirzepatide mitigates cognitive decline in zebrafish model of type 2 diabetes mellitus induced by high-fat diet
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Effect of TZP oncognitive impairment in zebrafish in old and young age groups in T-maze, A number of entries in favorable zone; B number of entries in unfavorable zone; C Time spent in favorable zone; D Time spent in unfavorable zone. After treatment with TZP time spent and number of entries in the unfavourable zone significantly decreased in both the age groups of zebrafish as compared to the HFD group. The statistical data analysis is presented by two-way ANOVA analysis by employing the Bonferroni post-test. Values presented as mean ± SD (p < 0.05), a vs. control, TZP (10 nM) per se, b vs. HFD, c vs. HFD + TZP (10 nM/kg) in both age groups. Values presented as mean ± SD (p < 0.05), α vs. HFD (young age group), β vs. HFD + TZP (young age group) (n = 12). A [F (4, 110) = 0.75, p = 0.5615], B [F (4, 110) = 0.25, p = 0.9093], C [F (4, 110) = 0.24, p = 0.9170], D [F (4, 110) = 1.74, p = 0.1466] |