FIGURE

FIGURE 4

ID
ZDB-FIG-250805-35
Publication
Bai et al., 2025 - Effects of realgar-indigo naturalis formula on a zebrafish tumor xenograft model induced by human acute promyelocytic leukemia cells: antitumor activity, hepatotoxicity, and transcriptomic analysis
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FIGURE 4

Integrated mechanisms of ATRA in APL therapy. Functional analyses identify key pathways mediating ATRA’s therapeutic effects: (A) GO analysis links ATRA to muscle contraction, creatine synthesis, and coagulation; (B) KEGG analysis highlights altered FoxO and PI3K-Akt signaling alongside apoptotic regulation; Gene Set Enrichment Analysis (GSEA) further validates FoxO (C) and apoptosis (D) as critical regulatory axes.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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