FIGURE

FIGURE 3

ID

ZDB-FIG-250805-34

Publication

Bai et al., 2025 - Effects of realgar-indigo naturalis formula on a zebrafish tumor xenograft model induced by human acute promyelocytic leukemia cells: antitumor activity, hepatotoxicity, and transcriptomic analysis

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FIGURE 3

Transcriptomic profiling of differentially expressed genes (DEGs) across treatment groups. (A–C) Volcano plots show DEGs under |log2FC| ≥ 1 and Q-value ≤0.05 thresholds for (A) ATRA-vs-Model (45 upregulated, red; 10 downregulated, green), (B) RIF-vs-Model (168 upregulated, red; 29 downregulated, green), and (C) Combination-vs-Model (385 upregulated, red; 189 downregulated, green). Dashed lines demarcate significance thresholds. (D) Venn diagram illustrates overlapping DEGs (n = 282) common to all three comparisons, indicating shared transcriptional perturbations.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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