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FIGURE 4

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ZDB-IMAGE-250805-36
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Figures for Bai et al., 2025
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Figure Caption

FIGURE 4

Integrated mechanisms of ATRA in APL therapy. Functional analyses identify key pathways mediating ATRA’s therapeutic effects: (A) GO analysis links ATRA to muscle contraction, creatine synthesis, and coagulation; (B) KEGG analysis highlights altered FoxO and PI3K-Akt signaling alongside apoptotic regulation; Gene Set Enrichment Analysis (GSEA) further validates FoxO (C) and apoptosis (D) as critical regulatory axes.

Acknowledgments
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