FIGURE

Fig. 4

ID

ZDB-FIG-250505-63

Publication

Shvartsburd et al., 2025 - Corticotropin-releasing hormone receptor 1 mediates the enhanced locomotor activity and metabolic demands to an acute thermal stress in adult zebrafish

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Fig. 4

Lack of Crhr1 affects the thermal stress-mediated swimming performance. (A) The SMR of WT and crhr1−/− fish measured in a swim tunnel respirometer during the 1-h acclimation at either 28°C or 33°C before the forced swim. This value was taken as the single lowest MO2 measurement during acclimation at a water flow speed of 4.5 cm/s. (B) MMR of fish taken as the single largest MO2 value measured during the forced swim test. (C) Aerobic scope of fish calculated as the MMR − SMR. (D) Ucrit of fish following the forced swim test, where water flow was slowly increased by 4.5 cm/s every 10 min until the fish collapsed against the back grate of the swim tunnel. Asterisks indicate significant main effects (Two-way ANOVA, *p < 0.05, **p < 0.01). Crhr1, corticotropin-releasing hormone receptor 1; KO, crhr1−/−; MMR, maximum metabolic rate; MO2, metabolic rate; SMR, standard metabolic rate; Ucrit, critical swimming speed; WT, wildtype.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT crhr1^ca403/ca403
Conditions:	heat shock water flow heat shock, water flow
Observed In:	whole organism aerobic respiration
Stage:	Adult

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Neuroendocrinol.