FIGURE

Fig. 5

ID

ZDB-FIG-250505-117

Publication

Chen et al., 2025 - G protein-coupled receptor GPR182 negatively regulates sprouting angiogenesis via modulating CXCL12-CXCR4 axis signaling

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Fig. 5

Whole-genome transcriptomic profiling of control embryos and gpr182 morphants. (A) Heatmaps based on bulk RNA-seq data represent the expressions of cardiovascular-related genes in 36 and 48 hpf embryos. Zebrafish cxcr4a, vegfaa, and esm1 are upregulated in gpr182 morphants. (B and C) Expression levels of cxcr4a, vegfaa, and esm1 are validated by qPCR and WISH. Data are presented as mean ± SD, with statistical significance determined by Student’s t-test. *, p < 0.05; **, p < 0.01; ***, p < 0.001

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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