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FIGURE 4

ID

ZDB-FIG-250401-5

Publication

Wu et al., 2025 - SB218078 inhibits angiogenesis and epithelial-mesenchymal transition in breast cancer

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FIGURE 4

SB218078 inhibits the growth of breast cancer cells in vitro. (A–C) SB218078 (1 μM and 2 μM) significantly inhibits colony formation in T47D and MDA-MB-231 cells. (D, E) Treatment with SB218078 (1 μM and 2 μM) for 72 h reduces the proliferation of T47D and MDA-MB-231 cells. (F, G) Treatment with SB218078 (1 μM and 2 μM) for 72 h promotes the cell apoptosis of T47D and MDA-MB-231 cells. (H–N) SB218078 (1 μM and 2 μM) also inhibits the migration and invasion of both T47D and MDA-MB-231 cells. Scale bar in (H, J, and L): 50 μm.

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