FIGURE

FIGURE 1

ID

ZDB-FIG-250401-2

Publication

Wu et al., 2025 - SB218078 inhibits angiogenesis and epithelial-mesenchymal transition in breast cancer

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FIGURE 1

SB218078 Inhibits Vascular Development in Zebrafish Embryos. (A, B) Representative images of intersegmental vessels (ISVs) in zebrafish embryos at 12 h post-fertilization (hpf) treated with vehicle control and various concentrations of SB218078 (1.25 μM, 2.5 μM, 5 μM, 10 μM). (C, D) Regeneration of amputated zebrafish fins was monitored over a 7-day period. *P < 0.05, **P < 0.005, ***P < 0.001. Scale bar in (A and C) 50 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT
Conditions:	chemical treatment by environment: vascular endothelial growth factor receptor antagonist amputation: caudal fin, chemical treatment by environment: vascular endothelial growth factor receptor antagonist
Observed In:	intersegmental vessel regenerating fin blood vessel
Stage Range:	5-9 somites to Days 30-44

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Pharmacol