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FIGURE 2

ID

ZDB-FIG-250401-3

Publication

Wu et al., 2025 - SB218078 inhibits angiogenesis and epithelial-mesenchymal transition in breast cancer

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FIGURE 2

SB218078 inhibits angiogenesis in vitro. (A, B) SB218078 (1 μM and 2 μM)) inhibits VEGF-induced tube formation in human umbilical vein endothelial cells (HUVECs). (C) Treatment with SB218078 (1 μM and 2 μM) for 72 h significantly reduces HUVEC proliferation. (D, F) SB218078 (1 μM and 2 μM) inhibits the formation of HUVEC colonies. (E, G–I) SB218078 also inhibits HUVEC migration and invasion. Scale bar in (A, F, and H): 50 μm.

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Acknowledgments

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