FIGURE

Figure 8

ID

ZDB-FIG-250219-41

Publication

Cerveró-Varona et al., 2025 - Amniotic epithelial Cell microvesicles uptake inhibits PBMCs and Jurkat cells activation by inducing mitochondria-dependent apoptosis

Other Figures

All Figure Page

Back to All Figure Page

Figure 8

Exposure of injured zebrafish larvae to AEC-derived MV stimulated early immune cell recruitment

(A) Illustration depicting the experimental plan followed for the treatment of 72 hpf zebrafish larvae with AEC ± LPS_MV and subsequent time lapse observation.

(B) Exemplary images of Tg(lysz:dsRed2) larvae post tail fin resection, showcasing the localization of immune cells in the tail and their accumulation at the site of injury from 0.5 to 6 hpd.

(C) Densitometric analysis of RFU, representing the amounts of immune cells detected in the total area and within the wounded area, normalized over CTR (black line). Data (mean ± SD) represent 3 independent sets of experiments (n = at least 3 biological replicates in each group per set). ∗, ∗∗ Statistically significant values between the different studied groups (p < 0.05, p < 0.01, respectively). One-way ANOVA was employed for comparing normally distributed data. Scale bar, 100 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ iScience