FIGURE
Fig. 1
- ID
- ZDB-FIG-250217-14
- Publication
- Spampinato et al., 2025 - Lactate accumulation promotes immunosuppression and fibrotic transformation of bone marrow microenvironment in myelofibrosis
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Fig. 1
High circulating lactate in MF sera favors immune deregulation. (A) Evaluation of Lactate concentration in PB from healthy and PMF patients. (B) Analysis of the percentage of Treg and (D) M-MDSCs after culturing healthy PBMCs with HC or PMF serum. (C) Evaluation of 10 μM AZD3965 effects on circulating lactate-induced Treg and (E) M-MDSC expansion. Data are presented as means ± SD. ***p < 0.001; ****p < 0.0001 |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
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