FIGURE

Fig. 3

ID

ZDB-FIG-250128-64

Publication

Revenu et al., 2024 - Myosin 1b regulates intestinal epithelial morphogenesis via interaction with UNC45A

Other Figures

All Figure Page

Back to All Figure Page

Fig. 3

MYO1B loss impairs membrane recycling and spindle orientation (A) Confocal sections of NT control, MYO1B KO, and MYO5B KO Caco-2 3D cultures stained for the lysosome marker LAMP1 and DAPI, and quantification of the percentage of vacuoles containing cells (Caco-2 NT n = 22, MYO1B KO n = 35, MYO5B KO n = 35). Scale bars, 20 ?m. (B) Confocal sections of NT control and MYO1B KO Caco-2 3D cultures stained for ?-tubulin and DAPI. The ? angle between the spindle axis and the substratum in the confocal x-z dimension was quantified in metaphase (Caco-2 NT n = 42, MYO1B KO n = 40, MYO5B KO n = 44). Scale bars, 20 ?m. Data are presented as median; one-way ANOVA test, ?p < 0.05, ??p < 0.01, ???p < 0.001, ????p < 0.0001.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Cell Rep.