FIGURE

Figure 2

ID

ZDB-FIG-250127-142

Publication

Chen et al., 2025 - Type 2 Diabetes Induces Mitochondrial Dysfunction in Zebrafish Skeletal Muscle Leading to Diabetic Myopathy via the miR-139-5p/NAMPT Pathway

Other Figures

All Figure Page

Back to All Figure Page

Figure 2

Skeletal muscle mass loss in zebrafish with type 2 diabetes mellitus (T2DM). (a) Hematoxylin and eosin (HE) staining of longitudinal sections of zebrafish tail skeletal muscle in each group, scale bar: 100 μm. The right side is an enlarged view of the red box on the left, scale bar: 20 μm. (b) Analysis of the total muscle fiber areas in each HE-stained section. (c) Analysis of the number of different muscle fiber areas in each HE-stained section. (d) Analysis of the difference in the muscle fiber area of the tail skeletal muscle in each group between 0 and 1500 μm² (small), 1501 and 3000 μm² (medium), and 3000 μm² and above (large). (e) EdU staining intensity of the skeletal muscle of zebrafish, indicating muscle proliferation and regeneration. EdU-labeled areas are indicated by the white arrows, scale bar: 500 μm. (f) Statistical chart of the positive area of EdU labeling. ** p < 0.01, *** p < 0.001. (n = 3 samples/group).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Int. J. Mol. Sci.