FIGURE

Fig. 4

ID

ZDB-FIG-241206-4

Publication

Smith et al., 2024 - Receptor tyrosine kinase inhibition leads to regression of acral melanoma by targeting the tumor microenvironment

Other Figures

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Fig. 4

Genetic characterization of AM and CM PDX tumor models. A Available AM PDX models encompass the spectrum of TCGA MAPK mutations. Relevant Tier I (pathogenic) and II (likely pathogenic) SNV mutations, MC1R mutations associated with melanoma predisposition, and CNV are represented in the tile plot. Black bars link PDX tumors that were collected from the same patient. B AM PDX models with localized highly amplified genomic regions are compared to a representative CM model

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Exp. Clin. Cancer Res.