FIGURE

Fig. 3

ID

ZDB-FIG-241206-3

Publication

Smith et al., 2024 - Receptor tyrosine kinase inhibition leads to regression of acral melanoma by targeting the tumor microenvironment

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Fig. 3

Histologic and tumor growth rate characterization of AM and CM PDX tumor models. A Anatomic location of AM and CM tumors. CM are labelled in blue text, acral subungal melanoma (ASM) in orange, and volar AM in red. B Representative clinical, low-passage, and high passage PDX tumor histology images. C-D Results from the Clinical Drift Score validation indicates that PDX tumors are histologically stable through multiple passages. Scores represent cytologic and histologic architecture drift from the original clinical tumor histology: none/identical (0), minimal (1), mild (2), moderate (3), and marked (4). Definitions and criteria for each classification are available in Supplemental Data 3. Four CM tumors and nine AM tumors are plotted in C-D. E Growth rates of representative PDX tumors

Expression Data

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Antibody Labeling

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Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Exp. Clin. Cancer Res.