ZFIN Image: Smith et al., 2024, Fig. 4

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Figure Caption

Fig. 4

Genetic characterization of AM and CM PDX tumor models. A Available AM PDX models encompass the spectrum of TCGA MAPK mutations. Relevant Tier I (pathogenic) and II (likely pathogenic) SNV mutations, MC1R mutations associated with melanoma predisposition, and CNV are represented in the tile plot. Black bars link PDX tumors that were collected from the same patient. B AM PDX models with localized highly amplified genomic regions are compared to a representative CM model

Acknowledgments

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