FIGURE

FIGURE 6

ID

ZDB-FIG-241017-109

Publication

Lee et al., 2024 - Transgenic zebrafish as a model for investigating diabetic peripheral neuropathy: investigation of the role of insulin signaling

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FIGURE 6

Depletion of insulin production downregulates the mTOR signaling pathway in the PLLg in ins:epNTR-mCherry zebrafish. (A–B”) Fluorescence images showing the PLLg and pS6⁺ cells in Ins:epNTR-mCherry expressing Tg (tubb2b:dsred) larvae treated with DMSO (A–A”) and MTZ (B–B”) at 9 dpf. (C) Quantification of the number of pS6⁺ PLLg cells from panels (A) and (B), *p = 0.0305, t-test (n = 10 larvae per group). Scale bar, 20 μm in (A).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front. Cell. Neurosci.