FIGURE

FIGURE 5

ID

ZDB-FIG-241017-108

Publication

Lee et al., 2024 - Transgenic zebrafish as a model for investigating diabetic peripheral neuropathy: investigation of the role of insulin signaling

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FIGURE 5

BMS-754807-induced IR inhibition reduces PLL nerve endings in ins:epNTR-mCherry zebrafish. (A–C). In-vivo fluorescence images showing sensory nerve endings in Ins:epNTR-mCherry expressing Tg (tubb2b:dsred) larvae treated with DMSO (A), MTZ, (B) and BMS-754807 (C) at 9 dpf. (D) Quantification of the number of axon bifurcation as depicted in panels (A–C), ****p < 0.0001, one-way ANOVA (n = 12 larvae in the DMSO group, n = 13 larvae in the MTZ group, and n = 16 larvae in the inhibitor group). Scale bar, 10 μm in (A).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front. Cell. Neurosci.