ZFIN Image: Lee et al., 2024, FIGURE 5

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Figure Caption

FIGURE 5

BMS-754807-induced IR inhibition reduces PLL nerve endings in ins:epNTR-mCherry zebrafish. (A–C). In-vivo fluorescence images showing sensory nerve endings in Ins:epNTR-mCherry expressing Tg (tubb2b:dsred) larvae treated with DMSO (A), MTZ, (B) and BMS-754807 (C) at 9 dpf. (D) Quantification of the number of axon bifurcation as depicted in panels (A–C), ****p < 0.0001, one-way ANOVA (n = 12 larvae in the DMSO group, n = 13 larvae in the MTZ group, and n = 16 larvae in the inhibitor group). Scale bar, 10 μm in (A).

Acknowledgments

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