FIGURE
Fig. 11
- ID
- ZDB-FIG-240910-49
- Publication
- García-Cuesta et al., 2024 - Allosteric modulation of the CXCR4:CXCL12 axis by targeting receptor nanoclustering via the TMV-TMVI domain
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Fig. 11
TMVI transition from inactive to active position. Ribbon representation of TMVI of CXCR4 structures superimposed for inactive (PDB code 3ODU), intermediate active (AGR1.135, AGR1.137) and active (PDB 8U4N) upon interaction with no, negative allosteric modulators and CXCL12-induced Gi-protein interaction, respectively. Arginine 235 is depicted in stick representation as a reference for the movement of the protein. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
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