IMAGE

Fig. 11

ID
ZDB-IMAGE-240910-49
Source
Figures for García-Cuesta et al., 2024
Image
Figure Caption

Fig. 11 TMVI transition from inactive to active position. Ribbon representation of TMVI of CXCR4 structures superimposed for inactive (PDB code 3ODU), intermediate active (AGR1.135, AGR1.137) and active (PDB 8U4N) upon interaction with no, negative allosteric modulators and CXCL12-induced Gi-protein interaction, respectively. Arginine 235 is depicted in stick representation as a reference for the movement of the protein.

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