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Fig. 5

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ZDB-FIG-240906-5

Publication

Wang et al., 2024 - Inhibition of mitochondrial citrate shuttle alleviates metabolic syndromes induced by high-fat diet

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Fig. 5

Slc25a1 inhibition enhances mitochondrial oxidative phosphorylation and proliferation in a high-fat diet (HFD). A and B: hepatic TCA cycle and oxidative phosphorylation-related gene expression and metabolites in zebrafish (n = 4 and 5–7, respectively). C: hepatic mtDNA in zebrafish (n = 6). D: mRNA expression of hepatic pgc1αa and pgc1αb in zebrafish (n = 5–7). E: mitochondrial metabolic patterns after inhibition of Slc25a1 under HFD. Values are means ± SD. The asterisk symbol indicates significant differences from the control treatment at *P < 0.05, **P < 0.01, ***P < 0.001 (independent-sample t test). Figure created with BioRender.com.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Am. J. Physiol. Cell Physiol.