FIGURE

Fig. 6

ID

ZDB-FIG-240906-6

Publication

Wang et al., 2024 - Inhibition of mitochondrial citrate shuttle alleviates metabolic syndromes induced by high-fat diet

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Fig. 6

Inhibition of Slc25a1 remodels protein acetylation modification in zebrafish liver under high-fat diet (HFD). A: hepatic acetyl-CoA content in zebrafish (n = 6). B: mRNA expression of hepatic sirts in zebrafish (n = 5–7). C: protein expression of hepatic Acss2 in zebrafish (n = 3). D and E: levels of pan-acetylation in zebrafish liver cell line (ZFL) and zebrafish liver. F: protein expression of hepatic ac-Cpa1a and ac-Pdhe1α in zebrafish (n = 2). G: hepatic acetyl-CoA content in Nile tilapia (n = 6). H: protein expression of hepatic ac-Cpa1a and ac-Pdhe1α in Nile tilapia (n = 2). I: the shift in acetylation paradigms after inhibition of Slc25a1 under HFD. Values are means ± SD. The asterisk symbol indicates significant differences from the control treatment at *P < 0.05, **P < 0.01, ***P < 0.001 (independent-sample t test). Figure created with BioRender.com.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Am. J. Physiol. Cell Physiol.