FIGURE

Fig. 6

ID
ZDB-FIG-240828-49
Publication
De Bortoli et al., 2024 - Somatic loss-of-function PIK3R1 and activating non-hotspot PIK3CA mutations associated with Capillary Malformation with Dilated Veins (CMDV)
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Fig. 6

PI3K?Akt?mTOR signaling and RAS?RAF?MAPK signaling in vascular anomalies. Inhibitors of the signaling pathway are shown in red: PIK3CA inhibitor alpelisib (BYL719), Akt inhibitor MK-2206, and mTOR inhibitor rapamycin (sirolimus). Akt, protein kinase B; ERK, extracellular signal?regulated kinase; MEK, MAPK/extracellular signal?regulated kinase; PI3K, phosphoinositide 3-kinase.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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