FIGURE

Figure 3

ID

ZDB-FIG-240822-35

Publication

Gawel et al., 2024 - Induction of seizures and initiation of epileptogenesis by pilocarpine in zebrafish larvae

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Figure 3

Effect of diazepam (DZP) on PILO-induced local field potential (LFP) events. Larvae were incubated in medium containing DZP (20 μM) for 20 h, and, subsequently, PILO was added to wells (final concentration = 50 mM). After 5 min incubation with PILO, LFPs recording were performed: (A) control recording of seizure-like events as presented on the graph evoked by PILO 50 mM; (B) representative LFP recordings performed in larvae exposed to DZP 20 μM + PILO 50 mM, note that in 3 out of 4 larvae, no seizure-like activity was recorded within 20 min of analysis, (C) only 2 short-lasting, low amplitude seizure-like events were found in larvae no. 3 within 20 min of analysis.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front. Mol. Neurosci.