FIGURE

Fig. 10

ID

ZDB-FIG-240802-39

Publication

Labudina et al., 2024 - Cohesin composition and dosage independently affect early development in zebrafish

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Fig. 10

Wnt stimulation rescues notochord width in stag2b−/−. (A-D) Expression pattern of tbxta in wild-type (A,C) and stag2b−/− (B,D) zebrafish tailbuds with (C,D) and without (A,B) Wnt stimulation (BIO). Images are maximum intensity projections of three (4.8 μm) optical sections. Scale bars: 20 μm. The number of embryos with each expression pattern out of the total analyzed is noted. (E) Violin plots with overlaid box plots visualizing measurements of notochord width. The box plot limits indicate the interquartile range (IQR) between the first quartile (Q1) and the third quartile (Q3), the horizontal line inside the box represents the median (second quartile, Q2), and the whiskers extend to the smallest and largest values within 1.5× the IQR from Q1 and Q3, respectively, with any points outside this range considered outliers. The x-axis indicates the genotype, treatment status and the number of embryos measured in each group. Significance was determined using an unpaired t-test: **P<0.01, ****P<0.0001. ns, not significant.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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