FIGURE

Fig. 5

ID

ZDB-FIG-240709-22

Publication

Xu et al., 2024 - ULI-ssDRIP-seq revealed R-loop dynamics during vertebrate early embryogenesis

Other Figures

All Figure Page

Back to All Figure Page

Fig. 5

Correlation between R-loops and enhancers during early development. A. Permutation test results of correlations between enhancers at dome stage (represented as dome-enhancer, GSE114954) and six R-loop clusters shown in Fig. 4B B. Scatter plot of R-loop levels at 256-cell and dome stages on enhancers overlapping with C5 R-loop (represented as C5+ dome-enhancers). Up, log2FC > 0.5 (dome/256-cell), red. Down, log2FC < −0.5 (dome/256-cell), blue. C. Scatter plot of RNA expression levels [log10(FPKM+1)] of genes regulated by C5+ dome-enhancers. “Regulated” was defined as the nearest genes from enhancers. Up, log2FC > 1 (dome/256-cell), red. Down, log2FC < −1 (dome/256-cell), blue. D. IGV snapshot of strand-specific ULI-ssDRIP-seq (upper) and RNA-seq (lower) signals around has2 gene at 256-cell and dome stages. C5 R-loop and dome-enhancer were shown. E. Gene Ontology (GO) biological process analysis results of genes regulated by dome-enhancers overlapping with each R-loop cluster (represented as Cn + dome-enhancers). The q values were shown.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Cell Insight