FIGURE

Fig. 2

ID

ZDB-FIG-240627-51

Publication

Berasain et al., 2024 - Accelerated evolution in the human lineage led to gain and loss of transcriptional enhancers in the RBFOX1 locus

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Fig. 2

Comparative expression assays in transgenic zebrafish. RBFOX1-HARs with (A) human-biased and (B) chimp-biased activity. A representative image of the expression pattern driven by the human sequence (Homo sapiens) and its chimpanzee ortholog (Pan troglodytes) is shown at 24, 48, and 72 hpf. (C) Bright-field and fluorescent reference images of wild-type zebrafish. Note that the yolk sac of zebrafish emits autofluorescence. Fb, forebrain; Mb, midbrain; Hb, hindbrain; SC, spinal cord; E, eye; H, heart; M, muscle. All transgenic lines analyzed are included in fig. S3, and higher-magnification images are shown in fig. S4.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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