FIGURE

Fig. 1

ID

ZDB-FIG-240618-1

Publication

Bondue et al., 2024 - MFSD12 depletion reduces cystine accumulation without improvement in proximal tubular function in experimental models for cystinosis

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Fig. 1

Basal MFSD12 mRNA levels are comparable between WT and CYS ciPTECs. A: ciPTECs were derived from the urine of three control individuals (WT) and eight patients with cystinosis with different CTNS genotypes. C(t)s are shown for GAPDH (left) and MFSD12 (right). Each dot represents a biological replicate and means with SE are shown. B: ?C(t)s were pooled from the WT ciPTECs and compared with the CYS ciPTECs (one-way ANOVA, ns = no significance). C(t), threshold cycle; CYS, cystinosis; ciPTEC, conditionally immortalized proximal tubular epithelial cell; WT, wild type.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Am. J. Physiol. Renal Physiol.