FIGURE
Fig. 4
- ID
- ZDB-FIG-240611-31
- Publication
- Ding et al., 2024 - Mycobacterial CpsA activates type I IFN signaling in macrophages via cGAS-mediated pathway
- Other Figures
- All Figure Page
- Back to All Figure Page
Fig. 4
CpsA-dependent type I IFNs and ISGs activation in vivo (A) Adult zebrafishes were infected with WT or ?cpsA Mm strains (104 CFU) and the mRNA levels of type I IFNs and ISGs of the fish body were determined by RT-qPCR and normalized to gapdh. (B) C57BL/6J mice were infected with WT, ?cpsA Mm strain (?3 × 108 CFU/mouse) via tail vein injection. The mRNA levels of type I IFNs and ISGs of the tail were determined by RT-qPCR. In A and B, data shown are mean fold increase over PBS-treated animals ± SEM. A, ?p < 0.05 by two-way ANOVA with multiple comparisons test, and B, ?p < 0.05 by unpaired t tests. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Full text @ iScience