FIGURE

Fig. 7.

ID

ZDB-FIG-240606-35

Publication

Kaliya-Perumal et al., 2024 - Genetic regulation of injury induced heterotopic ossification in adult zebrafish

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Fig. 7.

Analysis of thoracic intermuscular bone size following injury in kcnk5b^pfau/+ and il11ra^−/− mutants. (A) Representative images comparing the thoracic intermuscular bones on the uninjured and injured sides in kcnk5b^pfau/+ (n=24 bones/side from five fish) and its wild-type (WT) sibling controls (n=18 bones/side from five fish), as well as in il11ra^−/− (n=14 bones/side from four fish) and its WT sibling controls (n=14 bones/side from four fish). Scale bars: 200 µm. (B) Quantitative analysis revealed that the difference in size between uninjured and injured fins was more pronounced in the kcnk5b^pfau/+ mutants compared to that in their wild-type siblings. In contrast, the difference was minimal in il11ra^−/− mutants. Data show the mean±s.d. *P<0.05; **P<0.01; ***P<0.001 (two-tailed unpaired t-test for parametric data comparison; Mann-Whitney U test for non-parametric data comparison).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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