FIGURE

Figure 5.

ID

ZDB-FIG-240509-75

Publication

Cordero et al., 2024 - Leveraging chromatin state transitions for the identification of regulatory networks orchestrating heart regeneration

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Figure 5.

Transition from active to inactive chromatin state between 4 dpci and 14 dpci marks the start of the healing process. (A) Alluvial plot representing the dynamic chromatin states with reference point 14 dpci. (B) GO terms of the genes within the dynamic chromatin state groups presented in panel A. Example genes from each selected GO are presented to the right. The p-value was determined by enrichGO from clusterprofiler using ORA test; p-value *P < 0.05. (C) T-distributed stochastic neighbor embedding (t-SNE) visualization displaying the dynamic chromatin state transition groups (top) and the distribution of TF motifs (bottom). (D) Heatmap showing the enrichment of TF motifs in the clusters presented in (C, bottom panel). (E–H) Interaction network of TFs with enriched motifs in the largest cluster C1 associated with A_Ia transition (E), all clusters associated with A_Ia transition (F), with U_Ia transition (G) and cluster 3 associated with U_Pa transition (H) at 14 dpci.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

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Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Nucleic Acids Res.