FIGURE

FIGURE 6

ID

ZDB-FIG-240503-17

Publication

Zeng et al., 2024 - Zebrafish cobll1a regulates lipid homeostasis via the RA signaling pathway

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FIGURE 6

Loss of Cobll1a resulted in Abnormal Lipid Metabolism in Zebrafish. (A) Clustering heat maps of lipid anabolism-related genes in DEGs. WT and cobll1a mutated zebrafish embryo samples form two distinct groups. (B) RT-qPCR used to assess transcriptional expression level of lipid anabolism-related genes in cobll1a^−/− embryos at 52 hpf, compared with WT. (C) RT-qPCR analysis of transcriptional expression level of lipid catabolism-related genes in cobll1a^−/− embryos at 52 hpf, compared to the control. (D) At 4 dpf, fasn is expressed in adipocytes and the expression of fasn is up-regulated in cobll1a^−/− embryos. (E) At 5 dpf, Oil Red O staining was used to assess the lipid distribution and content of WT and cobll1a^−/− embryos.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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