FIGURE

FIGURE 3

ID

ZDB-FIG-240503-14

Publication

Zeng et al., 2024 - Zebrafish cobll1a regulates lipid homeostasis via the RA signaling pathway

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FIGURE 3

Depicts the abnormal liver development observed in the absence of cobll1a. (A) An RNA probe of fabp10a was utilized in situ hybridization of WT and cobll1a^−/− embryos at 4 dpf. (B–D) WT and cobll1a^−/− embryos at 4 dpf were detected with anti-sense RNA probes: intestinal marker fabp2(B), endocrine pancreatic marker insulin(C), and excretory pancreatic marker trypsin(D) through WISH. (E) The mRNA expression level of hepatopancreatic-intestinal development-related genes in WT and cobll1a^−/− embryos were analyzed using RT-qPCR at the 52 hpf stage.

Expression Data

Genes:	cp fabp2 fabp10a hhex ins prss1
Fish:	TU cobll1a^hn17/hn17 (TU)
Anatomical Terms:	endocrine pancreas exocrine pancreas intestine liver whole organism
Stage Range:	Long-pec to Day 4

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	cobll1a^hn17/hn17 (TU)
Observed In:	endocrine pancreas exocrine pancreas intestine liver whole organism
Stage Range:	Long-pec to Day 4

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Cell Dev Biol