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Lateral line regeneration does not change with age in zebrafish. (a) There is a significant effect of age when data are analyzed using the average number of hair cells (HCs) per caudal neuromast (mixed-effects model, F1,22 = 12.93, p = 0.0016 for the fixed effect of fish age), with significantly fewer hair cells in old fish at baseline and again 96 h after neomycin damage (Bonferroni-corrected posthoc t-test, **p < 0.01). (b) There is no age effect when data are normalized to the number of baseline hair cells for each fish (mixed-effects model, F1,22 = 0.2979, p = 0.5907 for the fixed effect of fish age). N = 8–12 fish/treatment, data are presented as mean ± 1 s.d. and dots represent individual fish. Note the lack of error bars for baseline values in b; each fish was set to 100%.
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