FIGURE

Figure S5.

ID

ZDB-FIG-240315-101

Publication

Pozo-Morales et al., 2024 - Starvation-resistant cavefish reveal conserved mechanisms of starvation-induced hepatic lipotoxicity

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Figure S5.

Lipofermata treatment does not impact animal growth, liver size in fed animals, or starvation resistance.

(A, B) Representative brightfield images (A) and quantification of body size (B) of 6 dpf zebrafish larvae treated with vehicle (0.01% DMSO) or 5 μM of lipofermata from 4 to 6 dpf without exogenous feeding. (C, D) MIP of the liver from Tg(fabp10a:EGFP) animals (C) and quantification of the liver area (D) of 8 dpf zebrafish larvae fed with rotifers from 5 dpf onward and treated with vehicle or lipofermata overnight from 6 to 8 dpf. ns, P > 0.05, t test. (E) Survival curves for zebrafish larvae treated with vehicle or lipofermata from 4 to 6 dpf without exogenous feeding.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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