FIGURE

Figure S4.

ID

ZDB-FIG-240315-100

Publication

Pozo-Morales et al., 2024 - Starvation-resistant cavefish reveal conserved mechanisms of starvation-induced hepatic lipotoxicity

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Figure S4.

Transcriptional changes in the liver of 6 dpf fasting zebrafish upon lipofermata treatment.

(A) Volcano plot depicts the changes in gene expression in the liver of 6 dpf fasting zebrafish upon 48 h of lipofermata treatment. Up- and down-regulated genes are colored in blue and orange, respectively. (B, C) Barplot displaying the changes in selected cell cycle–related genes (B) and cytokines (C). All the plotted genes display gene expression differences with a false discovery rate < 0.1. (D) Mean ± SEM of the number of macrophages normalized by the liver area in vehicle- and lipofermata-treated animals at 6 dpf under fasting conditions. Each point represents a single animal. ns, P > 0.05, t test.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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