FIGURE

Fig. 5

ID

ZDB-FIG-231215-60

Publication

Kawaguchi et al., 2019 - Co-option of the PRDM14-CBFA2T complex from motor neurons to pluripotent cells during vertebrate evolution

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Fig. 5

zPRDM14, but not sPRDM14, interacts with mCBFA2T2. (A) Co-IP analysis of each PRDM14 orthologue with TET2 and CBFA2T2. (B) ChIP-qPCR analysis of TET1 and TET2 binding at pluripotency-associated genes in wild-type ESCs or mPrdm14 KO ESCs expressing the empty vector, sPRDM14, zPRDM14 or mPRDM14. The enrichment of TET1 and TET2 are indicated by the percent input with the s.e.m. (two technical replicates). (C) ChIP-qPCR analysis of SUZ12 and H3K27me3 at Fgfr1 and Dnmt3b. The enrichment of SUZ12 and H3K27me3 are shown by the percent input with the s.e.m. (two technical replicates).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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