FIGURE

Figure 4

ID

ZDB-FIG-230731-11

Publication

Bulygin et al., 2023 - Inner Amino Acid Contacts Are Key Factors of Multistage Structural Rearrangements of DNA and Affect Substrate Specificity of Apurinic/Apyrimidinic Endonuclease APE1

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Figure 4

Changes in the FRET signal during the interaction of zAPE1 N253G (A), A254G (B), or E260A (C) enzyme with the F-substrate. [S] = 1.0 µM, enzyme concentrations are shown in the panels. Theoretical curves (smooth traces) were obtained by the global fitting procedure in the DynaFit 4 software.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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