FIGURE

Figure 7

ID

ZDB-FIG-230731-14

Publication

Bulygin et al., 2023 - Inner Amino Acid Contacts Are Key Factors of Multistage Structural Rearrangements of DNA and Affect Substrate Specificity of Apurinic/Apyrimidinic Endonuclease APE1

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Figure 7

Polyacrylamide gel electrophoresis (PAGE) analysis of product accumulation under the action of zAPE1 enzymes after 40 s for the DHU-substrate (A), 10 min for the dU-substrate (B), 60 min for the αA-substrate (C), and 30 min for the εA-substrate (D). [E] = 2.0 μM, [S] = 1.0 μM. Lane “Contr.” denotes DNA substrate mobility without the enzyme treatment.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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