FIGURE

Figure 2

ID

ZDB-FIG-230731-9

Publication

Bulygin et al., 2023 - Inner Amino Acid Contacts Are Key Factors of Multistage Structural Rearrangements of DNA and Affect Substrate Specificity of Apurinic/Apyrimidinic Endonuclease APE1

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Figure 2

(A) Kinetic curves of product accumulation in the course of F-substrate cleavage by the WT zAPE1 enzyme or by its mutants under steady-state conditions at [E] = 0.04 μM and [S] = 1.0 μM. (B) A comparison of observed rate constants (mean ± SD, s⁻¹) of the AP endonuclease reaction of the zAPE1 enzymes.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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