FIGURE

Fig. 5

ID

ZDB-FIG-230508-68

Publication

Yu et al., 2022 - Changes in aggression and locomotor behaviors in response to zinc is accompanied by brain cell heterogeneity and metabolic and circadian dysregulation of the brain-liver axis

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Fig. 5

Fig. 5. General hepatic transcriptome signature after zinc exposure. Venn diagrams and heatmap of DEGs (A and B); signature DEGs associated with antioxidant physiology and autophagy in ZnCl₂-low group (C and D) and antioxidant physiology in ZnCl₂-high group (E); significantly enriched and up-regulated functions in ZnCl₂-low and ZnCl₂-high groups (F); significantly enriched and down-regulated functions in ZnCl₂-low and ZnCl₂-high groups (G) The screening criteria of enrichment analyses were p < 0.01 with enrichment genes ≥ 5 or 0.05 < p ≤ 0.01 with enrichment genes ≥ 10. Details of enrichment analyses are shown in Table S4.

Expression Data

Genes:	ggt5a hmox2a hmox2b nfe2 selenoi
Fish:	AB
Condition:	chemical treatment by environment: zinc dichloride
Anatomical Term:	liver
Stage:	Adult

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB
Condition:	chemical treatment by environment: zinc dichloride
Observed In:	liver liver amino acid metabolic process liver apoptotic process liver carboxylic acid metabolic process liver cell cycle liver cellular response to reactive oxygen species liver circadian rhythm liver immune response
Stage:	Adult

Phenotype Detail

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