Gene
nfe2
- ID
- ZDB-GENE-030124-1
- Name
- nuclear factor, erythroid 2
- Symbol
- nfe2 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Enables protein heterodimerization activity. Contributes to sequence-specific DNA binding activity. Acts upstream of or within several processes, including otic vesicle morphogenesis; regulation of primitive erythrocyte differentiation; and swim bladder inflation. Part of transcription regulator complex. Is expressed in blood; otic placode; otic vesicle; ventral mesenchyme; and ventral mesoderm. Orthologous to human NFE2 (nuclear factor, erythroid 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 14 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu729 (12 images)
Wild Type Expression Summary
- All Phenotype Data
- 10 figures from 3 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR004826 | Basic leucine zipper domain, Maf-type |
| Domain | IPR004827 | Basic-leucine zipper domain |
| Family | IPR047167 | Nuclear Factor Erythroid-derived 2-like |
| Homologous_superfamily | IPR008917 | Transcription factor, Skn-1-like, DNA-binding domain superfamily |
| Homologous_superfamily | IPR046347 | Basic-leucine zipper domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Basic-leucine zipper domain | Basic leucine zipper domain, Maf-type | Basic-leucine zipper domain superfamily | Nuclear Factor Erythroid-derived 2-like | Transcription factor, Skn-1-like, DNA-binding domain superfamily |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M2B990 | InterPro | 466 | |||||
| UniProtKB:Q7ZZR2 | InterPro | 419 |
Interactions and Pathways
No data available
Plasmids
No data available