Fig. 5
Fig. 5
Fig. 5. General hepatic transcriptome signature after zinc exposure. Venn diagrams and heatmap of DEGs (A and B); signature DEGs associated with antioxidant physiology and autophagy in ZnCl2-low group (C and D) and antioxidant physiology in ZnCl2-high group (E); significantly enriched and up-regulated functions in ZnCl2-low and ZnCl2-high groups (F); significantly enriched and down-regulated functions in ZnCl2-low and ZnCl2-high groups (G) The screening criteria of enrichment analyses were p < 0.01 with enrichment genes ≥ 5 or 0.05 < p ≤ 0.01 with enrichment genes ≥ 10. Details of enrichment analyses are shown in Table S4.