Fig. 3
- ID
- ZDB-FIG-230508-11
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- Zhang et al., 2022 - Tumor-derived exosomal lincRNA ROR promotes angiogenesis in nasopharyngeal carcinoma
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Fig. 3. linc-ROR promotes angiogenesis in vitro and vivo. (A) The fluorescent transfection efficiency of HUVECs was captured by inverted microscope (scale bar: 100 ?m) (B) According to qRT-PCR results, linc-ROR level in HUVECs was depressed after transfecting shROR lentivirus compared with transfecting a negative control lentivirus. (C?H) The effect of linc-ROR on proliferation and migration of HUVECs were observed by CCK-8 assay (C), EDU assay (D, E), transwell assays (F, G), wound healing assay (H) (scale bar: 100 ?m). (I) Morphology of blood vessels in Tg (flila: EGFP) zebrafish embryos injected with exosomes from CNE2-NC and CNE2-shROR culture medium for 48h, 72h were captured by fluorescence microscope (scale bar: 500 ?m). (J) The images displayed were the amplification of SIVs (scale bar: 100 ?m). The photographs shown were representative of at least three independent experiments. All data show mean ± SD of at least three independent experiments. (*P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001). |
Reprinted from Molecular and Cellular Probes, 66, Zhang, S., Cai, J., Ji, Y., Zhou, S., Miao, M., Zhu, R., Li, K., Xue, Z., Hu, S., Tumor-derived exosomal lincRNA ROR promotes angiogenesis in nasopharyngeal carcinoma, 101868, Copyright (2022) with permission from Elsevier. Full text @ Mol. Cell. Probes