FIGURE

Fig. 1.

ID

ZDB-FIG-230119-36

Publication

Wang et al., 2022 - Variable phenotypes and penetrance between and within different zebrafish ciliary transition zone mutants

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Fig. 1.

Gross phenotype of cilia-related mutants and wild-type (WT) zebrafish across time. Lateral views of WT and mutant animals at 2 days post fertilization (dpf), 5 dpf, 3 weeks post fertilization (wpf) and >3 months post fertilization (mpf; adult). The penetrance of the imaged phenotype [curled-down tail (CDT) and/or scoliosis for most, a decreased head-trunk-angled defect (HTA) for mks1 and b9d2, and small size for tmem216] in −/− animals is indicated in the bottom right of each panel (P, observed/total number of −/− identified). At 3 wpf and in adults, we indicate the Mendelian inheritance (MI) in the bottom left of each panel. MI was calculated as % of the number of observed −/− divided by the expected number of −/− (1/3 of the sum of observed +/+ and +/−). Scale bars: 1000 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	b9d2^uab17/uab17 (AB) cc2d2a^uab16/uab16 (AB) cep290^uab18/uab18 (AB) ift88^tz288/tz288 ift172^uab11/uab11 (AB) mks1^uab12/uab12 (AB) nphp1^uab20/uab20 (AB) nphp4^uab21/uab21 (AB) rpgrip1l^uab15/uab15 (AB) tctn1^uab19/uab19 (AB) tmem67^uab14/uab14 (AB) tmem216^uab13/uab13 (AB) (all 12)
Observed In:	head post-vent region trunk vertebral column whole organism
Stage Range:	Long-pec to Adult

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Dis. Model. Mech.